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Recent Literature Review of microorganism Profile and Antibiogram of Neonatal Septicaemia in Tertiary Hospital

Journal of Advances in Microbiology and Biotechnology (JAMB), Available online 11th September 2017

Dr.S.Subathra devi | Dr.Lakshmi sarayu


Background: Infant blood poisoning may be a clinical syndrome of bacteraemia characterized by general signs and symptoms in initial month of life. The kind and pattern of organisms that cause infant infection changes over time and vary from one hospital to a different hospital, even within the same country. Early identification and correct management of infant blood poisoning will bring down the morbidity and mortality considerably. Objectives: 1) To isolate and determine the microorganism etiologic agents to blame for infant infection. 2) To check and distinction the rife microorganism pathogens isolated from early onset infant infection (EOS) and late onset infant infection (LOS). 3) To access risk factors related to infant infection. 4) To work out the condition pattern of isolates to the normally used antimicrobial agents within the treatment of infection. Methodology: Blood culture reports were studied in 306 cases of clinically suspected septicemia in neonate’s victimization the quality technique of Mackie and Sir James Paul McCartney. The antibiotic sensitivity was performed by Kirby-Bauer's disc diffusion technique. Risk factors for infection within the kids furthermore as mothers were registered. Results: Blood culture reports were positive in eighty two.35% of cases. Thirty 3 babies (79%) had early onset infection and nine (21%) had late onset infection. Enterobacteria pneumonia and system were the most common organisms inflicting infant infection in each Eos and LOS. immatureness, lbw and metabolic process distress syndrome were powerfully related to blood culture well-tried infant infection. Maternal risk factors known were preterm labour, promenade and intrapartum fever. Conclusion: The spectrum of organisms that cause infant infection changes over time and varies from region to region. These organisms have additionally developed increasing multi-drug resistance over the last twenty years. So information of the pattern of microorganism isolates and their antimicrobial condition pattern is helpful for prompt treatment of patients.